British pair celebrate after birth of first cloned puppy of its genu

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West Yorkshire couple Laura Jacques and Richard Remde mobilized South Korean firm offering dog-cloning work for PS 67,000

A British pair have constructed biography after a surrogate bird-dog committed delivery to the first cloned puppy of its manner on Boxing Day.

In the first case of its kind, the boxer puppy was cloned from the couples dead pup, Dylan, almost two weeks after it died. The previous limit for puppy cloning was five days after death.

Laura Jacques, 29, and Richard Remde 43, from West Yorkshire, were grief stricken after their boxer expired at the age of eight in June, having been diagnosed the beginning of this year with a intelligence tumour.

The pair decided to try to clone Dylan and recruited the services of the controversial Sooam Biotech Research Foundation, which offers a commercial-grade dog-cloning busines for $100,000( PS67, 000) per procedure. It is the only laboratory of its category in the world. They have heralded the birth as a miracle.

The male puppy has been appointed Chance, after a reference in Jacques favourite film, Disneys Homeward Bound. He is expected to be joined in three working days season by a second cloned puppy this one is likely to be mentioned Shadow after another attribute in the film.

Jacques said she and Remde were overwhelmed after witnessing the birth by caesarian section on Saturday in the operating theatre at Sooam.

Dylan,

Dylan, who perished in June this year. Photo: Christopher Thomond for the Guardian

The whole circumstance simply seems surreal, she said. I lost all sense of era. I have no idea how long everything took, the whole situation obligated me feel very disoriented. I was just grasping on to Richard for about an hour and a half after Chance was born.

After they went him out I still couldnt fairly believe it had happened. But formerly he started obliging rackets I knew it was real. Even as a puppy of just a few minutes old-time I cant belief how much he looks like Dylan. All the colourings and structures on his body are in exactly the same homes as Dylan had them.

Remde said: I was much more overwhelmed with feeling at the birth than I expected to be.

The couple said the puppy was feeding well from his mother. Im trying to get my chief round the fact that this puppy has 100% of the same DNA as Dylan, said Jacques. Its quite confusing but Im telling myself that Chance is similar to one of Dylans puppies.

I had had Dylan since he was a puppy, she said. I fathered him so much better, he was my baby, my child, my entire world.

Sooam, the leading laboratory in the world for pup cloning, has created more than 700 bird-dogs for commercial clients. The technique commits embed DNA into a blank pup egg that has had the nucleus removed.

Jacques heard about dog cloning from a documentary about a competition Sooam ranged for one UK dog owner to have their pup cloned free of charge. Rebecca Smith was the win and her dachshund, Winnie, who is still alive, was successfully cloned.

David Kim, research scientists at Sooam, said the birth of the two cloned hounds was eliciting for the lab because tests were taken away from Dylan 12 periods after he died. This is the first case we have had where cells have been taken from a dead hound after a very long time, he said. Hopefully it will allow us to extend the time after fatality that we can take cadres for cloning.

There are no regulations on the cloning of domesticateds, although the cloning of human beings is illegal, and in August the European parliament elections voted to proscribe the cloning of farm animals.

Hwang Woo-suk, one of the leading investigates at the Sooam laboratory, is a controversial flesh. In 2004, he produced studies and research group at Seoul University, in South Korea, which claimed to have created a cloned human embryo in a test tube. An independent scientific committee knew no evidence of this and in January 2006 the journal Science, which had originally published the research, forswore it. He was part of the team delivering the cloned puppy on Boxing Day.

The RSPCA expressed concern about puppy cloning. A spokesperson said: There are serious ethical and welfare concerns relating to the application of cloning technology to animals. Cloning swine necessitates terms and conditions that lawsuit pain and distress, with extremely high lack and mortality rates. There is also a body of proof that cloned animals frequently abide physical ailments such as tumors, pneumonia and abnormal proliferation patterns.

Jacques, a dog baby-walker, and Remde, who runs a construct fellowship, Heritage Masonry& Conservation, had to take two determines of samples from their dead hound after the first place of tests did not grow in the lab. Remde drew two tours in quick succession to South Korea to deliver the cadre samples. They are now waiting for the proposed establishment of the second largest puppy and are hoping to adopt the puppies two surrogate the women and deliver four pups back to the UK next July after the quarantine point has ended.

Key years in the cloning of Dylan

11 June : Couple told their eight-year-old boxer hound Dylan has an inoperable brain cancer. They were told he might live for up to 18 months with treatment.

30 June : Dylan croaks after a cardiac arrest. 1& 2 July : Vet allows the couple to deter Dylan with them for a few days before implanting him. Jacques starts experimenting their chances of cloning a dead dog. 2 July : Dylan is chilled in a funeral parlour. Couple acquire medical paraphernalium from Boots to take a skin sample from Dylan to send to Sooam in South Korea in the hope that they can clone him. 4 July : Remde flies to South Korea with the samples, extradites them to laboratory staff awaiting at the airport and immediately goes on an aircraft back to the UK. 5 July : Dylans remains are frozen until a date is fixed for his burial. 6 July : Sooam says it does not repute the samples Remde has winged to South Korea could be used to create a cloned puppy. 7 July : Sooam asks whether the couple still have the dog and if so whether the government has want to try to obtain more tests for cloning. 10 July : The duet struggle to take samples from Dylan, whose mas abides frozen before burial. A small sample of cadres is eventually self-assured around midnight. 11 July : Remde flies to South Korea again to deliver the tests. Sooam receives the cadres having never attempted to clone a hound 12 daytimes after its death.

21 t October: Sooam substantiates the cells have grown to a sufficient degree that the cloning process could start.

23 November : Sooam says a pregnancy has been verified.

24 November : Sooam says a second pregnancy has been verified.

26 December: First boxer puppy is stand on Boxing Day.

29 December : Second puppy due.

Read more: www.theguardian.com

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